Endocrine Abstracts

Objective: To find consensus on issues that may raise clinical doubts in the management of patients with acromegaly in Spain.Methods: Nominal group and Delphi methodology was followed. Four experts on acromegaly were selected, who defined important clinical questions in the management of acromegaly. A set recommendations were proposed to solve these questions. Subsequently, a group of 30 additional endocrinologits from all over Spain was selected accordi...

Objectives: To evaluate the efficacy, safety and patient’s pain perception of percutaneous ethanol injection treatment (PEIT) as an alternative to surgery in symptomatic thyroid cysts.Patients and methods: Thirty consecutive patients (mean age: 46±10 years; 82% women) with symptomatic thyroid cysts relapsed after drainage were included. In all cases, cytology prior to treatment, maximum cyst diameter and volume were determined. PEIT was conduct...

Introduction: Silent corticotroph tumours (SCT) are a pituitary tumours (PT) subtype of corticotroph lineage that do not clinically express Cushing disease. Inmunohistochemical (IHC) studies reveal no differences between SCT and functioning corticotroph tumours with Cushing Syndrome (FCT). However, the silencing mechanisms of this type of tumours are not fully understood.Aim: In an important series of SCT, to sequence the POMC gene and quantify ...

Aim: To study the prevalence of metabolic syndrome (MS) and its relation with ghrelin in old men.Material and methods: Prospective-population based study (2002–2005) in which 153 independently living men older than 70 y were included. Comorbidities, physical exam, BMI, blood pressure were recorded and blood sample taken for biochemical and hormonal determinations. Metabolic syndrome was defined using IDF criteria.Results: MS w...

Introduction: Advanced differentiated thyroid carcinoma (aDTC) – herein defined as locally unresectable or metastatic disease – is one of the most common late-stage endocrine neoplasias. However, available data about its natural history is limited. ERUDIT is a multicenter, observational, retrospective study of patients diagnosed with aDTC in Spain and Portugal. The study describes its natural history from the initial diagnosis until the advanced stages of disease, ...